• Significant improvement in body contour with multiple cycles of CoolSculpting: This study demonstrated that an intensive regimen of CoolSculpting across various body areas significantly improves body contouring outcomes, with no adverse events reported, showcasing the safety and effectiveness of multiple treatment cycles (McKeown & Payne, 2021).
• Evolution of the treatment approach to cryolipolysis using the CoolAdvantage® applicator family: Transitioning from the CoolCore system to CoolAdvantage increased treatment versatility and number of cycles per treatment without compromising safety, indicating an advancement in cryolipolysis technology and its application (Gualdi et al., 2021).
• High Participant Satisfaction Achieved Using Cryolipolysis for Fat Reduction of the Abdomen and Flanks: A study reported high levels of patient satisfaction with cryolipolysis treatment outcomes for fat reduction in the abdomen and flanks, emphasizing the importance of managing patient expectations for enhancing satisfaction levels (Tan et al., 2021).
• Adverse Events Associated With Cryolipolysis: A systematic review detailed common adverse events such as treatment site erythema and numbness, and more severe complications like paradoxical adipose hyperplasia, underscoring the necessity for clinicians to be prepared to manage these outcomes (Hedayati et al., 2020).

These studies contribute to the growing body of evidence supporting the effectiveness and safety of CoolSculpting as a noninvasive option for body contouring, while also emphasizing the importance of understanding and managing potential adverse events.